Professor Handyside is an internationally-recognized pioneer and expert in human embryology and preimplantation genetics with an extensive research portfolio, a track record for innovation in single-cell diagnostics, and 20 years of experience in management in the private IVF sector in the UK. He developed the first transgenic mouse knockout of the HPRT gene using embryonic stem cells as a model of the human X-linked inherited disease, Lesch-Nyhan Syndrome, and achieved the first pregnancies worldwide following in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD) of inherited disease in 1990. He was the first Chairman of the European Society for Human Reproduction and Embryology (ESHRE) Special Interest Group in Reproductive Genetics, co-founder and first chairman of the ESHRE PGD Consortium and Past President of Preimplantation Genetic Diagnosis International Society (PGDIS). Professor Handyside is Scientific Director at the University of Kent in Canterbury, UK, and President and Co-Founder of ISRG.